Autonomic Ganglia Neuronal Density and Synaptic Structure in Chronic Experimental Autoimmune Autonomic Ganglionopathy
نویسندگان
چکیده
منابع مشابه
Autonomic ganglia neuronal density and synaptic structure in chronic experimental autoimmune autonomic ganglionopathy.
A utoimmune autonomic ganglionopathy (AAG) is a severe form of acquired autonomic failure. Symptoms include orthostatic hypotension, gastrointestinal dysmotility, dry mouth and eyes, impaired pupillary constriction, and blunted heart rate responses. While some patients have distal paresthesias or other sensory symptoms, objective evidence of somatic neuropathy is rare. Autoimmune autonomic gang...
متن کاملAutonomic ganglia, acetylcholine receptor antibodies, and autoimmune ganglionopathy.
Nicotinic acetylcholine receptors (AChR) are ligand-gated cation channels that are present throughout the nervous system. The ganglionic (alpha3-type) neuronal AChR mediates fast synaptic transmission in sympathetic, parasympathetic and enteric autonomic ganglia. Autonomic ganglia are an important site of neural integration and regulation of autonomic reflexes. Impaired cholinergic ganglionic s...
متن کاملTransient neonatal autoimmune autonomic ganglionopathy
Autoimmune autonomic ganglionopathy (AAG) is an acquired reversible neuroimmunologic disorder of autonomic ganglia in the sympathetic, parasympathetic, and enteric nervous systems. Antibodies specific for ganglionic nicotinic acetylcholine receptors (gAChRs) impair fast synaptic transmission between preganglionic and postganglionic neurons. Clinical manifestations of AAG reflect peripheral auto...
متن کامل[Autoimmune autonomic ganglionopathy and acute autonomic and sensory neuropathy].
Autonomic neuropathies may occur primarily or secondarily to various underlying diseases. Primary autonomic neuropathies are divided into pure autonomic neuropathy, autonomic neuropathy with sensory impairment, and autonomic neuropathy with sensory and motor impairment based on the concomitance or absence of sensory or motor dysfunctions. Autoimmune autonomic ganglionopathy refers to a pure aut...
متن کاملAutoimmune autonomic ganglionopathy: a possible postganglionic neuropathy.
OBJECTIVE To evaluate postganglionic autonomic and somatic nerve fiber involvement in a patient with chronic autoimmune autonomic ganglionopathy. DESIGN Case report. SETTING Department of Neurological Sciences, University Federico II of Naples. PATIENT A patient with a 16-year history of severe autonomic failure and a high nicotinic acetylcholine receptor antibody titer underwent an exten...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2011
ISSN: 0003-9942
DOI: 10.1001/archneurol.2011.52